Barcelona opened the scoring in the first half, with Lewandowski converting from the spot after Bruno Fernandes dragged Alejandro Balde to the ground.
Manchester United struck swiftly after the break, as Fred found the bottom corner from outside the box. Antony found the winner 16 minutes from time, sending a shot spiraling into the bottom corner to seal a 2-1 victory (4-3 on aggregate).
Barca had one last chance, but Raphael Varane cleared Lewandowski's shot off the line deep into stoppage time - enough to knock the Blaugrana out of European competition early.
GOAL rates Barcelona's players from Old Trafford...